Ceramide C6-d7
Based on 1 Customer Validation
Ceramide C6-d7 is the deuterium labeled Ceramide C6. Ceramide C6, a Ceramide pathway activator, is an exogenous short-chain ceramide which can induce apoptosis of multiple cancer cells.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.0%
- CAS No.: 2692624-22-7
- 화학식: C24H40D7NO3
- 분자량:404.68
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보관:
Solution, -20°C, 2 years
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
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HY-100355S1
C18-Ceramide-d7 -
HY-116258S
C16 Ceramide-d7 (d16:1,C16:0) -
HY-152022S
EOS (d18:1/32:0/18:2)-d9 -
HY-141580S1
C18 Dihydroceramide-d3-1 -
HY-152020S
Sphingosine-d9 (d18:1) -
HY-141629S2
N-Palmitoyl-D-sphingomyelin-d9 -
HY-134508S
C24-Ceramide-d7 -
HY-134575S
C24:1-Ceramide-d7 -
HY-100355S
C18-Ceramide-d3 -
HY-W698686S
β-Galactosyl-C18-ceramide-d35 -
HY-116392B
DL-threo-PDMP hydrochloride -
HY-N7745S2
Glucosylsphingosine-13C6
Biological Activity
제품 설명
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
신청
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2692624-22-7
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Unlabeled CAS 124753-97-5
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Appearance Liquid
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분자량 404.68
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화학식 C24H40D7NO3
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Color Colorless to light yellow
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SMILES
OC[C@@H]([C@@H](/C=C/CCCCCCCCCCC([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])O)NC(CCCCC)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Solution, -20°C, 2 years
순도&문서
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Data Sheet (268 KB)
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SDS (737 KB)
- English - EN (737 KB)
- Français - FR (737 KB)
- Deutsch - DE (737 KB)
- Norwegian - NO (737 KB)
- Español - ES (737 KB)
- Swedish - SV (737 KB)
- Italian - IT (737 KB)
- Korean - KR (737 KB)
- Portuguese - PT (737 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Qiu L, et al. C6-ceramide induces salivary adenoid cystic carcinoma cell apoptosis via IP3R-activated UPR and UPR-independent pathways. Biochem Biophys Res Commun. 2020;525(4):997-1003. [Content Brief]
[3]. Liu L, et al. C6-ceramide treatment inhibits the proangiogenic activity of multiple myeloma exosomes via the miR-29b/Akt pathway. J Transl Med. 2020;18(1):298. Published 2020 Aug 3. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ceramide C6-d7 Related Classifications
HY-19542S Related Classifications
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