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Cat. No.: HY-180792

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CK-571

CK-571 is a potent and selective inhibitor of smooth muscle myosin-2 (SMM), with an IC₅₀ value of 86 nM. CK-571 exhibits IC₅₀ values for cardiac muscle myosin (CMM), skeletal muscle myosin (SKM), and non-muscle myosin-2A (NMM-2A) of 2.3, 42, and 0.58 μM, respectively. CK-571 can be used for research on asthma, chronic obstructive pulmonary disease, and other smooth muscle-related diseases.

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CAS No.: 1119536-89-8
화학식: C₂₄H₂₆ClFN₄O₅
분자량:504.94

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

CK-571 Chemical Structure

CAS No.: 1119536-89-8

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Myosin Isoforms :

MLCK

Chemical Information

CAS No. 1119536-89-8
분자량 504.94
화학식 C₂₄H₂₆ClFN₄O₅
SMILES

O=C(OC[C@H](C[C@@H](O)CO)N(C)C(NCC1=C(Cl)C(F)=CC=C1)=O)NC2=NC=C3C(C=CC=C3)=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Suthar SK, et al. Fragment-based structure-activity relationship analysis of CK-571 reveals non-interacting groups drive smooth muscle myosin selectivity. Eur J Med Chem. 2025 Dec 16;305:118476. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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CK-571

All Myosin Isoforms