COX-2-IN-52
COX-2-IN-52 (Compound 5l) is an orally active and selective COX-2 inhibitor with an IC50 of 54 nM. COX-2-IN-52 can inhibit the release of NO in cells and has anti-inflammatory activity. COX-2-IN-52 has high gastrointestinal safety and can be used in the research of oral anti-inflammatory drugs.
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- 화학식: C16H13IN4O4S2
- 분자량:516.33
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
COX-2 54 nM (IC50) |
COX-1 15.98 μM (IC50) |
Chemical Information
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분자량 516.33
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화학식 C16H13IN4O4S2
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SMILES
O=C(O)CSC1=NN=C(C2=CC=C(S(=O)(N)=O)C=C2)N1C3=CC=C(I)C=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)