Dimethoate-d6
Based on 1 Customer Validation
Dimethoate-d6 is the deuterium labeled Dimethoate. Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active acetylcholinesterase inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice.
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- Purity: 99.86%
- CAS No.: 1219794-81-6
- 화학식: C5H6D6NO3PS2
- 분자량:235.29
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1219794-81-6
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Unlabeled Cas 60-51-5
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Appearance Solid
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분자량 235.29
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화학식 C5H6D6NO3PS2
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Color White to off-white
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SMILES
S=P(OC([2H])([2H])[2H])(SCC(NC)=O)OC([2H])([2H])[2H]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
순도&문서
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Data Sheet (270 KB)
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SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Korean - KR (420 KB)
- Portuguese - PT (420 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. CASIDA JE, et al. Toxic hazard from formulating the insecticide dimethoate in methyl 'Cellosolve'. Nature. 1961;189:507-508. [Content Brief]
[3]. Martínez-Morcillo S, et al. The organophosphorus pesticide dimethoate decreases cell viability and induces changes in different biochemical parameters of rat pancreatic stellate cells. Toxicol In Vitro. 2019 Feb;54:89-97. [Content Brief]
[4]. Nazam N, et al. Dimethoate Induces DNA Damage and Mitochondrial Dysfunction Triggering Apoptosis in Rat Bone-Marrow and Peripheral Blood Cells. Toxics. 2020 Oct 1;8(4):80. [Content Brief]
[5]. Aly NM, et al. Effect of dimethoate on the immune system of female mice. J Environ Sci Health B. 2000 Jan;35(1):77-86. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dimethoate-d6 Related Classifications
HY-B1946S Related Classifications
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