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Cat. No.: HY-171190

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ELQ-316

ELQ-316 is an endochinlike quinolone compound and an anti-parasite agent. ELQ-316 demonstrates a great efficacy against acute and chronic experimental toxoplasmosis.

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CAS No.: 1354745-69-9
화학식: C₂₄H₁₇F₄NO₄
분자량:459.39

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

ELQ-316 Chemical Structure

CAS No.: 1354745-69-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

ELQ-316 is an endochinlike quinolone compound and an anti-parasite agent. ELQ-316 demonstrates a great efficacy against acute and chronic experimental toxoplasmosis^[1].

All Parasite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	>10 μM Compound: 18b, ELQ-316	Inhibition of human cytochrome bc1 complex derived from HEK293 cell mitochondria using 50 uM decylubiquinol as substrate Inhibition of human cytochrome bc1 complex derived from HEK293 cell mitochondria using 50 uM decylubiquinol as substrate	[PMID: 24720377]
HepG2	IC₅₀	>10 μM Compound: 18b, ELQ-316	Cytotoxicity against human HepG2 cells after 24 hrs incubation by Alamar Blue assay Cytotoxicity against human HepG2 cells after 24 hrs incubation by Alamar Blue assay	[PMID: 24720377]

Chemical Information

CAS No. 1354745-69-9
분자량 459.39
화학식 C₂₄H₁₇F₄NO₄
SMILES

O=C1C2=CC(F)=C(C=C2NC(C)=C1C3=CC=C(OC4=CC=C(C=C4)OC(F)(F)F)C=C3)OC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Alday PH, et al. Genetic Evidence for Cytochrome b Qi Site Inhibition by 4(1H)-Quinolone-3-Diarylethers and Antimycin in Toxoplasma gondii. Antimicrob Agents Chemother. 2017 Jan 24;61(2):e01866-16. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
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수량:
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ELQ-316

All Parasite Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

ELQ-316 Related Classifications

HY-171190 Related Classifications