Ganoderic acid R
Ganoderic acid R is a potent anticancer agent. Ganoderic acid R inhibits the growth by inducing apoptosis on tumor cell line. Ganoderic acid R possesses significant cytotoxicity on a multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and a sensitive tumor cell line (KB-A-1).
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- CAS No.: 103963-39-9
- 화학식: C34H50O6
- 분자량:554.76
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | IC50 |
32 μM
Compound: 41
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Cytotoxicity against African green monkey Vero cells by GFP based microplate assay
Cytotoxicity against African green monkey Vero cells by GFP based microplate assay
|
[PMID: 28504879] |
In Vitro
Ganoderic acid R (0-50 µg/mL, 48 h) inhibit the growth by inducing apoptosis on tumor cell lines at the concentrations that more than 20 µg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:KB-A-1/Dox cells
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Concentration:0, 25, 50 μg/mL
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Incubation Time:48 h
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Result:Induced the cellular apoptosis, the number of apoptotic cells was increased from 35% to 90% during 48 h.
Chemical Information
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CAS No. 103963-39-9
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분자량 554.76
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화학식 C34H50O6
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SMILES
C[C@@]12C3=CC[C@](C)([C@@](CC4)([H])[C@H](C)[C@@H](OC(C)=O)C/C=C(C)/C(O)=O)[C@]4(C)C3=CC[C@@]1([H])C(C)([C@@H](CC2)OC(C)=O)C
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Structure Classification
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)