Glutaminase
Based on 1 Customer Validation
Glutaminase is a metabolic enzyme. Glutaminase catalyzes the hydrolysis of glutamine to glutamate. Glutaminase isoenzymes are encoded by Gls and Gls2 genes. Proteins GLS and GLS2 have different kinetic, immunologic, and molecular characteristics. Glutaminase can be used in the research of cancer.
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- CAS No.: 9001-47-2
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
3.5.1.2
50 - 200 U/mg protein
One unit is defined as the amount of enzyme that will deaminate 1.0 μmole of L-glutamine per min at pH 4.9 at 37°C
Chemical Information
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CAS No. 9001-47-2
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Appearance Solid
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Color Off-white to light yellow
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SMILES
[Glutaminase]
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Synonyms
GLS
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
용액&용해도
H2O : 1 mg/mL (Need ultrasonic and warming)
순도&문서
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Data Sheet (264 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Handling Instructions (2659 KB)
References
[1]. Wang JB, et al. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell. 2010 Sep 14;18(3):207-19. [Content Brief]
[2]. Matés JM, et al. Glutaminase isoenzymes in the metabolic therapy of cancer. Biochim Biophys Acta Rev Cancer. 2018 Dec;1870(2):158-164. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glutaminase Related Classifications
HY-P2760 Related Classifications
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