GRL093-22
Based on 1 Customer Validation
GRL093-22 is a potent and selective G protein-coupled receptor kinase (GRK) inhibitor, with IC50s of 60 and 40 nM for GRK5 and GRK6, respectively. GRL093-22 has the potential for the research of heart failure and multiple myeloma.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.51%
- CAS No.: 3113391-19-5
- 화학식: C33H29FN6O3
- 분자량:576.62
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 3113391-19-5
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Appearance Solid
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분자량 576.62
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화학식 C33H29FN6O3
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Color Yellow to orange
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SMILES
FC1=CC=C([C@H](NC(C2=CC=C(NC(/C3=C\C4=C(C)C(NC(C5=C(C)N=C6N5C=CC=C6)=O)=C(C)N4)=O)C3=C2)=O)C)C=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 25 mg/mL (43.36 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7342 mL | 8.6712 mL | 17.3424 mL | 43.3561 mL |
| 5 mM | 0.3468 mL | 1.7342 mL | 3.4685 mL | 8.6712 mL | |
| 10 mM | 0.1734 mL | 0.8671 mL | 1.7342 mL | 4.3356 mL | |
| 15 mM | 0.1156 mL | 0.5781 mL | 1.1562 mL | 2.8904 mL | |
| 20 mM | 0.0867 mL | 0.4336 mL | 0.8671 mL | 2.1678 mL | |
| 25 mM | 0.0694 mL | 0.3468 mL | 0.6937 mL | 1.7342 mL | |
| 30 mM | 0.0578 mL | 0.2890 mL | 0.5781 mL | 1.4452 mL | |
| 40 mM | 0.0434 mL | 0.2168 mL | 0.4336 mL | 1.0839 mL |