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Cat. No.: HY-172677

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IIP0943

IIP0943 is a selective inhibitor of PLK1 (polo-like kinase 1), with an IC₅₀ of 5.1 nM for PLK1. In addition, IIP0943 exhibits antiproliferative activity against HCT116 cells, with an IC₅₀ of 0.22 µM. These results suggest that IIP0943 holds promise for research in the field of cancer therapeutics.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3040106-93-9
화학식: C₂₆H₂₈N₆O₃S
분자량:504.60

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

IIP0943 Chemical Structure

CAS No.: 3040106-93-9

사이즈

가격

재고

수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

PLK1

5.1 nM (IC₅₀)

All Polo-like Kinase (PLK) Isoforms :

Chemical Information

CAS No. 3040106-93-9
분자량 504.60
화학식 C₂₆H₂₈N₆O₃S
SMILES

CN1CCN(C2=CC(NC3=NC=C(C)C(OC4=CC=CC5=C4SC(C(N)=O)=C5)=N3)=C(OC)C=C2)CC1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xie W, et al. Accelerating discovery of bioactive ligands with pharmacophore-informed generative models. Nat Commun. 2025 Mar 10;16(1):2391. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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Purity:
수량:

IIP0943

All Polo-like Kinase (PLK) Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

IIP0943 Related Classifications

HY-172677 Related Classifications