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Cat. No.: HY-142074

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Inophyllum B

(Synonyms: (+)-Inophyllum B)

Inophyllum B ((+)-Inophyllum B) is a potent HIV Reverse Transcriptase inhibitor with an IC₅₀ value of 38 nM. Inophyllum B inhibits HIV-1 (IC₅₀=1.4 μM) in vitro cell culture. Inophyllum B can be isolated from the acetone extract of the giant African snail, Achatina fulica.

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CAS No.: 41135-06-2
화학식: C₂₅H₂₄O₅
분자량:404.46

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Inophyllum B Chemical Structure

CAS No.: 41135-06-2

사이즈

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

HIV-1

1.4 μM (IC₅₀)

Reverse Transcriptase

38 nM (IC₅₀)

All HIV Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
MOLT-4	IC₅₀	1.4 μM Compound: 2a (inophyllum B)	Anti-HIV activity against HIV-1 in Molt-4 cells using 7-day infective assay Anti-HIV activity against HIV-1 in Molt-4 cells using 7-day infective assay	[PMID: 7506311]
MOLT-4	IC₅₀	55 μM Compound: 2a (inophyllum B)	Tested for cytotoxicity in Molt-4 cells by XTT assay Tested for cytotoxicity in Molt-4 cells by XTT assay	[PMID: 7506311]

Chemical Information

CAS No. 41135-06-2
분자량 404.46
화학식 C₂₅H₂₄O₅
SMILES

O[C@@H]1C2=C(O[C@@H]([C@H]1C)C)C(C=CC(C)(O3)C)=C3C(C(C4=CC=CC=C4)=C5)=C2OC5=O
Synonyms

(+)-Inophyllum B
Structure Classification
- Phenylpropanoids
- Coumarins
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Patil AD, et al. The inophyllums, novel inhibitors of HIV-1 reverse transcriptase isolated from the Malaysian tree, Calophyllum inophyllum Linn. J Med Chem. 1993 Dec 24;36(26):4131-8. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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수량:
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CAS No.:
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Purity:
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Inophyllum B

All HIV Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Inophyllum B Related Classifications

HY-142074 Related Classifications