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Cat. No.: HY-P10845

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KRL74

KRL74 is a cyclic peptide inhibitor for interaction between the p6 domain of the HIV Gag protein and the UEV domain of the human TSG101 protein(p6/UEV) with an IC₅₀ of 5.44 μM and a K_d of 11.9 μM. KRL74 inhibits the budding process of HIV from host cells with an IC₅₀ of 2 μM in virus-like particle (VLP) budding assay.

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CAS No.: 2423969-43-9
화학식: C₅₀H₆₁ClN₁₀O₉
분자량:981.53

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

KRL74 Chemical Structure

CAS No.: 2423969-43-9

사이즈

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All HIV Isoforms :

Chemical Information

CAS No. 2423969-43-9
분자량 981.53
화학식 C₅₀H₆₁ClN₁₀O₉
Sequence

cyclo(Ser-Gly-Trp-Ile-{Phe<4-Cl>}-Trp-Ala-Val)
Sequence Shortening

cyclo(SGWI-{Phe<4-Cl>}-WAV)
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lennard KR, et al., Development of a Cyclic Peptide Inhibitor of the p6/UEV Protein-Protein Interaction. ACS Chem Biol. 2019 Sep 20;14(9):1874-1878. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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KRL74

All HIV Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

KRL74 Related Classifications

HY-P10845 Related Classifications