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Cat. No.: HY-108564

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L 655240

L 655240 is thromboxane antagonist. L 655240 attenuates early ischemia- and reperfusion-induced arrhythmias in a canine model of coronary artery occlusion. L 655240 also involves in cancer and autoimmune disorders.

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CAS No.: 103253-15-2
화학식: C₂₁H₂₁ClFNO₂
분자량:373.85

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

L 655240 Chemical Structure

CAS No.: 103253-15-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
- In Vivo
Chemical Information
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Biological Activity

제품 설명

All Prostaglandin Receptor Isoforms :

In Vitro

L 655240 (7 nM) inhibits endoperoxide-induced aggregation in human paltelets^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

L 655240 (0.3 mg/kg; i.v.; single dose) changes heat rate, arterial and pulmonary arterial blood pressure, and cardiac output in canine model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 103253-15-2
분자량 373.85
화학식 C₂₁H₂₁ClFNO₂
SMILES

O=C(O)C(C)(C)CC(N1CC2=CC=C(Cl)C=C2)=C(C)C3=C1C=CC(F)=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wainwright CL, et al. The effects of L655,240, a selective thromboxane and prostaglandin endoperoxide antagonist, on ischemia- and reperfusion-induced cardiac arrhythmias. J Cardiovasc Pharmacol. 1988 Sep;12(3):264-71. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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- In Vitro
- In Vivo
Chemical Information
순도&문서
References

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L 655240

All Prostaglandin Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

L 655240 Related Classifications

HY-108564 Related Classifications