LE 28
Based on 1 publication(s) in Google Scholar
LE 28 is a selective and activity-dependent legumain probe. LE 28 becomes fluorescent only upon binding active legumain. LE 28 can be used for research of cancers and inflammatory diseases.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1416080-97-1
- 화학식: C102H111N10O21S3+
- 분자량:1909.22
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) LE 28
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Biological Activity
LE 28 (2 mg/kg, i.v.) signal is detected around the periphery of the tumors at 30 min, with maximal contrast between tumor and normal tissue achieved after 7 hours in HCT-116 xenograft tumor model[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:HCT-116 xenograft tumor model[1]
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Dosage:2 mg/kg
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Administration:i.v.
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Result:Detected the signal around the periphery of the tumors in as early as 30 min, with maximal contrast between tumor and normal tissue achieved after seven hours, and the signal remained constant up to 28 h.
Chemical Information
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CAS No. 1416080-97-1
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분자량 1909.22
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화학식 C102H111N10O21S3+
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SMILES
O=S(C1=C(C=CC=C1)C2=C(C=CC(N3C4=CC=CC=C4CC3)=C5)C5=[O+]C6=C2C=CC(N7C8=CC=CC=C8CC7)=C6)(N9CCC(CC9)C(NCCCNC(C%10=CC(C)=C(C(C)=C%10)C(OCC([C@H](CC(O)=O)NC([C@H]%11N(CCC%11)C([C@H](CCC(O)=O)NC(CCCCC[N+]%12=C(/C=C/C=C/C=C%13N(C%14=CC=C(S(=O)(O)=O)C=C%14C\%13(C)C)CC)C(C)(C)C%15=CC(S(=O)([O-])=O)=CC=C%12%15)=O)=O)=O)=O)=O)=O)=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LE 28 Related Classifications
HY-149102 Related Classifications
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