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Cat. No.: HY-172996

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NNRT-IN-8

NNRT-IN-8 (compound 9K) is a potent non-nucleoside reverse transcriptase inhibitor with EC₅₀ values of 0.0014, 0.0041, 0.0077 µM for WT HIV-1, K103N, E138K, respectively.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₇H₂₈N₆O₂
분자량:468.55

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

NNRT-IN-8 Chemical Structure

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

NNRT-IN-8 (compound 9K) is a potent non-nucleoside reverse transcriptase inhibitor with EC₅₀ values of 0.0014, 0.0041, 0.0077 µM for WT HIV-1, K103N, E138K, respectively^[1].

IC₅₀ & Target^[1]

HIV-1 (WT)

0.0014 μM (EC₅₀)

RT-K103N

0.0041 μM (EC₅₀)

HIV-1 (E138K)

0.0077 μM (EC₅₀)

All HIV Isoforms :

Chemical Information

분자량 468.55
화학식 C₂₇H₂₈N₆O₂
SMILES

CC1=CC(/C=C/C#N)=CC(C)=C1OC2=CC=NC(NC3=CC=C(C=C3)CN4CCN(CC4)C=O)=N2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ji X, et al. Discovery of novel diarypyrimidine derivatives as potent HIV-1 NNRTIs by exploiting the tolerant region I within NNRTI binding pocket. Eur J Med Chem. 2025 Oct 5;295:117787. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

NNRT-IN-8

All HIV Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

NNRT-IN-8 Related Classifications

HY-172996 Related Classifications