ONT-993
Based on 1 Customer Validation
ONT-993 is an aliphatic hydroxylated metabolite. ONT-993 inhibits CYP2D6 (IC50=7.9 µM) and causes metabolism-dependent inactivation of CYP3A (KI=1.6 µM).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.85%
- CAS No.: 937263-81-5
- 화학식: C26H24N8O3
- 분자량:496.52
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
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CYP2D6 7.9 μM (IC50) |
Chemical Information
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CAS No. 937263-81-5
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Appearance Solid
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분자량 496.52
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화학식 C26H24N8O3
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Color White to off-white
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SMILES
OCC1(C)N=C(NC2=CC3=C(NC4=CC=C(C(C)=C4)OC5=CC6=NC=NN6C=C5)N=CN=C3C=C2)OC1
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Synonyms
AR 00440993
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 50 mg/mL (100.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (269 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0140 mL | 10.0701 mL | 20.1402 mL | 50.3504 mL |
| 5 mM | 0.4028 mL | 2.0140 mL | 4.0280 mL | 10.0701 mL | |
| 10 mM | 0.2014 mL | 1.0070 mL | 2.0140 mL | 5.0350 mL | |
| 15 mM | 0.1343 mL | 0.6713 mL | 1.3427 mL | 3.3567 mL | |
| 20 mM | 0.1007 mL | 0.5035 mL | 1.0070 mL | 2.5175 mL | |
| 25 mM | 0.0806 mL | 0.4028 mL | 0.8056 mL | 2.0140 mL | |
| 30 mM | 0.0671 mL | 0.3357 mL | 0.6713 mL | 1.6783 mL | |
| 40 mM | 0.0504 mL | 0.2518 mL | 0.5035 mL | 1.2588 mL | |
| 50 mM | 0.0403 mL | 0.2014 mL | 0.4028 mL | 1.0070 mL | |
| 60 mM | 0.0336 mL | 0.1678 mL | 0.3357 mL | 0.8392 mL | |
| 80 mM | 0.0252 mL | 0.1259 mL | 0.2518 mL | 0.6294 mL | |
| 100 mM | 0.0201 mL | 0.1007 mL | 0.2014 mL | 0.5035 mL |
ONT-993 Related Classifications
HY-151239 Related Classifications
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