Piriprost
Piriprost (U-60257) is an inhibitor of Glutathione-S-transferase and leukotriene biosynthesis inhibitor. Piriprost inhibits the biosynthesis of leukotriene C/D without affecting cyclooxygenase-mediated arachidonic acid metabolites. Piriprost increases the activity of alkaline phosphatase (ALP). Piriprost antagonizes contractions induced by leukotriene C/D in vitro. Piriprost is used in asthma research.
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- CAS No.: 79672-88-1
- 화학식: C26H35NO4
- 분자량:425.57
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 79672-88-1
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분자량 425.57
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화학식 C26H35NO4
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SMILES
C(CCCC(O)=O)C=1N(C2=C(C1)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C2)C3=CC=CC=C3
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Synonyms
U-60257
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. van der Meer JW, et al. Abstract!. The Netherlands journal of medicine. 2002 Dec;60(11):418. [Content Brief]
[2]. Cejic SS, et al. Examination of the effects of piriprost (U-60,257B) on alkaline phosphatase activity of rat endometrial stromal cells in vitro. Prostaglandins. 1991 Aug;42(2):179-89. [Content Brief]
[3]. McCormack DG, et al. The contrasting influence of two lipoxygenase inhibitors on hypoxic pulmonary vasoconstriction in anesthetized pigs. Am Rev Respir Dis. 1989 Jan;139(1):100-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)