Polyoxin D

Polyoxin D (0.4 mM; 24 h or 48 h post-inoculation) inhibits fungal growth in Pinto leaves, and compared with oxycarboxin treatment, treatment at 24 hr allows more infection sites to develop necrotic cells and lobed, non-fluorescent haustoria, suggesting their continued survival^[1].
Polyoxin D (0.4 mM; 24 h or 48 h post-inoculation) results in a higher incidence of necrotic cells in the incompatible interaction with cultivar 765, especially when applied at 48 h^[1].
Polyoxin D (0.4 mM; 24 h or 48 h post-inoculation) causes haustorial collapse and encasement by callose-like material at 24 hr, whereas treatment at 48 hr leads to haustorial wall thickening (100-140 nm) and a slightly electron-opaque extrahaustorial matrix (30-70 nm) in the compatible interaction^[1].
Polyoxin D (0.4 mM; 24 h or 48 h post-inoculation) induces shriveled infected hyphae, silica deposition, and thick-walled (130-190 nm) lobed haustoria at 24 hr, whereas treatment at 48 hr has a lesser effect in incompatible interactions^[1].
Polyoxin D (20-120 μM; 16 h) inhibits the elongation of isolated stipes of Coprinus cinereus when administered by microinjection^[3].
Polyoxin D, as a chitin synthase inhibitor, is a useful tool for studying the effects of chitin synthesis on the morphological development of germinating Mucor rouxii spores^[5].
Polyoxin D affects the germination and morphological development of Trichoderma viride ^[5].
Polyoxin D inhibits the growth of both the mycelial and yeast-like forms of Mucor rouxii without significantly affecting its dimorphism^[5].

Polyoxin D (0.02-2 mM; 16 h) inhibits the elongation of isolated stipes and fruiting bodies of Coprinus cinereus when applied by basal immersion^[3].

Polyoxin D inhibits S. calcitrans chitin synthase with an I₅₀ of 1 mM, and this differential sensitivity is related to its K_m for UDP-GlcNAc^[4].
Polyoxin D causes the accumulation of UDP-GlcNAc in cultured cockroach leg regenerates^[4].
Polyoxin D inhibits chitin synthase in cell-free systems from S. calcitrans and T. castaneum^[4].