PSB069
Based on 1 Customer Validation
PSB069 bearing a p-chlorophenylamino residue is a potent, well-tolerated and nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.5%
- CAS No.: 78510-31-3
- 화학식: C20H12ClN2NaO5S
- 분자량:450.83
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보관:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
제품 설명
IC50 & Target
Ki: 16~18 μM (NTPDases1, 2, 3)[1]
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NG108-15 | IC50 |
20 μM
Compound: 16
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Antagonist activity at mouse P2Y2 receptor in mouse NG108-15 cells assessed as inhibition of UTP-induced calcium mobilization
Antagonist activity at mouse P2Y2 receptor in mouse NG108-15 cells assessed as inhibition of UTP-induced calcium mobilization
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[PMID: 18006312] |
In Vitro
PSB069 is a nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 78510-31-3
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Appearance Solid
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분자량 450.83
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화학식 C20H12ClN2NaO5S
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Color Pale purple to purple
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SMILES
O=S(C(C(N)=C1C2=O)=CC(NC3=CC=C(Cl)C=C3)=C1C(C4=C2C=CC=C4)=O)(O[Na])=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
In Vitro:
DMSO : 45 mg/mL (99.82 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2181 mL | 11.0907 mL | 22.1813 mL | 55.4533 mL |
| 5 mM | 0.4436 mL | 2.2181 mL | 4.4363 mL | 11.0907 mL | |
| 10 mM | 0.2218 mL | 1.1091 mL | 2.2181 mL | 5.5453 mL | |
| 15 mM | 0.1479 mL | 0.7394 mL | 1.4788 mL | 3.6969 mL | |
| 20 mM | 0.1109 mL | 0.5545 mL | 1.1091 mL | 2.7727 mL | |
| 25 mM | 0.0887 mL | 0.4436 mL | 0.8873 mL | 2.2181 mL | |
| 30 mM | 0.0739 mL | 0.3697 mL | 0.7394 mL | 1.8484 mL | |
| 40 mM | 0.0555 mL | 0.2773 mL | 0.5545 mL | 1.3863 mL | |
| 50 mM | 0.0444 mL | 0.2218 mL | 0.4436 mL | 1.1091 mL | |
| 60 mM | 0.0370 mL | 0.1848 mL | 0.3697 mL | 0.9242 mL | |
| 80 mM | 0.0277 mL | 0.1386 mL | 0.2773 mL | 0.6932 mL |
PSB069 Related Classifications
HY-103262 Related Classifications
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