Sinitrodil
Sinitrodil (ITF 296) is an orally active organic nitrate with anti-ischaemic effect. Sinitrodil can be used for acute and chronic heart diseases research.
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- CAS No.: 143248-63-9
- 화학식: C10H10N2O5
- 분자량:238.20
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Pharmacokinetic parameters of Sinitrodil in rats[2]
| Route | Parameter | Value |
| IV (1 mg/kg) | CL (L/h/kg) | 2.7 |
| AUC (μg h/mL) | 0.37 | |
| T1/2 (h) | 3.85 | |
| PO (5 mg/kg) | Tmax (h) | 0.17 |
| T1/2 (h) | 1.95 | |
| Cmax (μg/mL) | 2.099 | |
| CL (L/h/kg) | 2.69 | |
| AUC (μg h/mL) | 1.364 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 143248-63-9
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분자량 238.20
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화학식 C10H10N2O5
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SMILES
O=C1C2=CC=CC=C2OCN1CCO[N+]([O-])=O
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Synonyms
ITF 296
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)