TL13-22
Based on 1 Customer Validation
TL13-22 is a negative control for TL13-12 (HY-122582) and a potent ALK inhibitor with an IC50 of 0.54 nM. TL13-22 does not degrade ALK in cells.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.71%
- CAS No.: 2229036-65-9
- 화학식: C45H55ClN10O9S
- 분자량:947.50
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Kinase Inhibitor Library
HY-L009
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Protein Tyrosine Kinase Compound Library
HY-L016
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Anti-Cancer Compound Library
HY-L025
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Heterocyclic Compound Library
HY-L138
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Membrane Protein-targeted Compound Library
HY-L149
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Serine/Threonine Kinase Inhibitor Library
HY-L164
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Anti-Brain Cancer Compound Library
HY-L188
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Protein Kinase Compound Library
HY-L196
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
IC50: 0.54 nM (ALK)[1]
Chemical Information
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CAS No. 2229036-65-9
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Appearance Solid
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분자량 947.50
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화학식 C45H55ClN10O9S
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Color Light yellow to yellow
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SMILES
O=C(NCCOCCOCCN1CCN(C2=CC=C(NC3=NC=C(Cl)C(NC4=CC=CC=C4S(=O)(C(C)C)=O)=N3)C(OC)=C2)CC1)CNC5=CC=CC(C(N6C7C(NCCC7)=O)=O)=C5C6=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 250 mg/mL (263.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0554 mL | 5.2770 mL | 10.5541 mL | 26.3852 mL |
| 5 mM | 0.2111 mL | 1.0554 mL | 2.1108 mL | 5.2770 mL | |
| 10 mM | 0.1055 mL | 0.5277 mL | 1.0554 mL | 2.6385 mL | |
| 15 mM | 0.0704 mL | 0.3518 mL | 0.7036 mL | 1.7590 mL | |
| 20 mM | 0.0528 mL | 0.2639 mL | 0.5277 mL | 1.3193 mL | |
| 25 mM | 0.0422 mL | 0.2111 mL | 0.4222 mL | 1.0554 mL | |
| 30 mM | 0.0352 mL | 0.1759 mL | 0.3518 mL | 0.8795 mL | |
| 40 mM | 0.0264 mL | 0.1319 mL | 0.2639 mL | 0.6596 mL | |
| 50 mM | 0.0211 mL | 0.1055 mL | 0.2111 mL | 0.5277 mL | |
| 60 mM | 0.0176 mL | 0.0880 mL | 0.1759 mL | 0.4398 mL | |
| 80 mM | 0.0132 mL | 0.0660 mL | 0.1319 mL | 0.3298 mL | |
| 100 mM | 0.0106 mL | 0.0528 mL | 0.1055 mL | 0.2639 mL |
TL13-22 Related Classifications
HY-136194 Related Classifications
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