Ulicyclamide
Ulicyclamide is a cytotoxic cyclic peptide found in the tunicate Lissoclinum patella.Ulicyclamide inhibits DNA and RNA synthesis in leukemia cells. Ulicyclamide can be used for the research of leukemia.
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- CAS No.: 74839-81-9
- 화학식: C33H39N7O5S2
- 분자량:677.84
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
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Biological Activity
Ulicyclamide (dose-response curve range; 48 h) is cytotoxic against cultured L1210 mouse leukemia cells in vitro, with an IC50 of 13 μg/mL after 48 h of incubation[1].
Ulicyclamide (dose-response curve range; 2 h) potently inhibits both DNA and RNA syntheses (IC50 = 2.2 μg/mL for each) in cultured L1210 mouse leukemia cells after 2 hr of incubation, while having no effect on protein synthesis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 74839-81-9
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분자량 677.84
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화학식 C33H39N7O5S2
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SMILES
O=C(N1CCC[C@]1(C2=N[C@]([H])3[C@H](O2)C)[H])[C@@H](NC(C4=CSC([C@H](NC(C5=CSC([C@@H](NC3=O)[C@@H](C)CC)=N5)=O)C)=N4)=O)CC6=CC=CC=C6
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ulicyclamide Related Classifications
HY-182258 Related Classifications
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