Urea-15N2
Based on 1 Customer Validation
Urea-15N2 is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
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- Purity: 99.80%
- CAS No.: 2067-80-3
- 화학식: CH415N2O
- 분자량:62.04
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
용액&용해도
DMSO : 100 mg/mL (1611.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (269 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Bennion BJ, et al. The molecular basis for the chemical denaturation of proteins by urea. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5142-7. [Content Brief]
[3]. Pan M, et al. Urea: a comprehensive review of the clinical literature. Dermatol Online J. 2013 Nov 15;19(11):20392. [Content Brief]
[4]. Wang H, et al. Urea. Subcell Biochem. 2014;73:7-29. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 16.1186 mL | 80.5932 mL | 161.1863 mL | 402.9658 mL |
| 5 mM | 3.2237 mL | 16.1186 mL | 32.2373 mL | 80.5932 mL | |
| 10 mM | 1.6119 mL | 8.0593 mL | 16.1186 mL | 40.2966 mL | |
| 15 mM | 1.0746 mL | 5.3729 mL | 10.7458 mL | 26.8644 mL | |
| 20 mM | 0.8059 mL | 4.0297 mL | 8.0593 mL | 20.1483 mL | |
| 25 mM | 0.6447 mL | 3.2237 mL | 6.4475 mL | 16.1186 mL | |
| 30 mM | 0.5373 mL | 2.6864 mL | 5.3729 mL | 13.4322 mL | |
| 40 mM | 0.4030 mL | 2.0148 mL | 4.0297 mL | 10.0741 mL | |
| 50 mM | 0.3224 mL | 1.6119 mL | 3.2237 mL | 8.0593 mL | |
| 60 mM | 0.2686 mL | 1.3432 mL | 2.6864 mL | 6.7161 mL | |
| 80 mM | 0.2015 mL | 1.0074 mL | 2.0148 mL | 5.0371 mL | |
| 100 mM | 0.1612 mL | 0.8059 mL | 1.6119 mL | 4.0297 mL |
Urea-15N2 Related Classifications
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