WIN 62577
WIN 62577 is a species-selective tachykinin NK1 receptor antagonist. WIN 62577 is also an allosteric enhancer with micromolar potency at M3 receptors. WIN 62577 exhibits potent antiviral activity against SARS-CoV-2.
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- CAS No.: 138091-43-7
- 화학식: C29H31N3O
- 분자량:437.58
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 138091-43-7
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분자량 437.58
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화학식 C29H31N3O
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SMILES
C[C@@]12[C@]3([H])[C@](CCC1=CC4=NC5=NC6=CC=CC=C6N5C=C4C2)([H])[C@@]7([H])[C@](CC3)([C@](O)(CC7)C#C)C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Briejer MR, et, al. Substance P-induced contractions of the guinea-pig proximal colon through stimulation of post-junctional tachykinin NK1 receptors. Eur J Pharmacol. 1993 Nov 30;250(1):181-3. [Content Brief]
[2]. Lazareno S, et, al. Progress toward a high-affinity allosteric enhancer at muscarinic M1 receptors. J Mol Neurosci. 2003;20(3):363-7. [Content Brief]
[3]. Singh A, et, al. Structural and Mechanistic Insights into the Main Protease (Mpro) Dimer Interface Destabilization Inhibitor: Unveiling New Therapeutic Avenues against SARS-CoV-2. Biochemistry. 2025 Apr 1;64(7):1589-1605. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
WIN 62577 Related Classifications
HY-169501 Related Classifications
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