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Cat. No.: HY-178501

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KRAS-IN-45

KRAS-IN-45 (Compound 1.019) is a KRAS inhibitor. KRAS-IN-45 can be used for the study of cancers.

For research use only. We do not sell to patients.

Formula: C₃₂H₃₃ClF₂N₈O₃
Molecular Weight:651.11

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

KRAS-IN-45 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

KRAS-IN-45 (Compound 1.019) is a KRAS inhibitor. KRAS-IN-45 can be used for the study of cancers^[1].

All Ras Isoforms :

Chemical Information

Molecular Weight 651.11
Formula C₃₂H₃₃ClF₂N₈O₃
SMILES

F[C@H]1CN(CCC2)[C@]2(COC3=NC4=C(F)C(C5=C(C=NN6)C6=CC(Cl)=C5[C@H]7C[C@H]7CCOC(N[C@@H]8CCN9C8)=O)=NC=C4C9=N3)C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ryan Paul Wurz, et al, MACROCYCLIC COMPOUNDS AS MODULATORS OF KRAS AND USES THEREOF CROSS REFERENCE TO PRIOR APPLICATIONS. WO2025194057A1.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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KRAS-IN-45

All Ras Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

KRAS-IN-45 Related Classifications

HY-178501 Related Classifications