2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. KRAS-IN-50

KRAS-IN-50 (Compound 136a) is a KRAS inhibitor. KRAS-IN-50 has an anti-proliferative effect on KRAS mutant cells. KRAS-IN-50 has anti-cancer activity against colon cancer.

For research use only. We do not sell to patients.

KRAS-IN-50

KRAS-IN-50 Chemical Structure

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KRAS-IN-50 Related Antibodies

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K-Ras H-Ras N-Ras Ras

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Description

KRAS-IN-50 (Compound 136a) is a KRAS inhibitor. KRAS-IN-50 has an anti-proliferative effect on KRAS mutant cells. KRAS-IN-50 has anti-cancer activity against colon cancer[1].

IC50 & Target[1]

K-RAS

 

Molecular Weight

640.78

Formula

C35H44N8O4
SMILES

N#CC1=C(N)C=CC2=C1[C@@]3(CCC2)CCCC4=C3ON=C4C5=NC(O[C@@H](C)[C@@H]6[C@@H](OC)CCN6C)=CC(N7CCNC8(COC8)C7)=N5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KRAS-IN-50 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRAS-IN-50RasGP2DSW620Anti-proliferationInhibitorinhibitorinhibit

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HY-180607
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