KRAS-IN-67
KRAS-IN-67 is a KRAS G12V inhibitor that exhibits low permeability. KRAS-IN-67 binds to the switch-II pocket and inhibits the function of mutant KRAS, with a target Kd of 2.4 nM for KRAS G12V. KRAS-IN-67 can be used for research on KRAS-driven cancers.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C28H35N9O4S
- Masse moléculaire:593.70
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
KRas G12V 2.4 nM (Kd) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 593.70
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Formule C28H35N9O4S
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SMILES
C[C@@H]([C@H]1N(C)CCC1)OC2=NC(C3=NOC([C@@]4(CCO5)CCCC6=C4C(C#N)=C(N)S6)=N3)=NC(N(C)CCNC5=O)=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KRAS-IN-67 Related Classifications
HY-191442 Related Classifications
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