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KRASG12D-IN-5

KRASG12D-IN-5 (Compound 241) is an orally active KRAS(G12D) inhibitor with an IC50 of 11 nM. KRASG12D-IN-5 has potent anticancer activity with no significant cytotoxicity against BxPC-3 (WT), KRAS mutation AsPC-1 (G12D) and MIAPaCa-2 cells (G12C) with CC50s of 10.37, 0.76 and 0.3 μM, respectively. KRASG12D-IN-5 can be used for cancer research, such as lung, pancreatic and colorectal cancer.

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  • CAS 番号: 2933935-13-6
  • 分子式: C34H31F5N6O2
  • 分子量:650.64
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • KRASG12D-IN-5 Chemical Structure
    KRASG12D-IN-5 構造式
CAS 番号: 2933935-13-6
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  • KRASG12D-IN-5 Chemical Structure
    KRASG12D-IN-5 Chemical Structure
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  • KRASG12D-IN-5