KSQ-4279 gentisate
Based on 1 publication(s) in Google Scholar
KSQ-4279 (gentisate) (Compound Formula I) is a potent USP1 inhibitor and a selective PARP1 inhibitor. KSQ-4279 (gentisate) is promising for research of cancers.
For research use only. We do not sell to patients.
- Purity: 99.75%
- CAS No.: 2938991-80-9
- Formula: C34H31F3N8O5
- Molecular Weight:688.66
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) KSQ-4279 gentisate
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Biological Activity
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USP1 |
PARP1 |
Chemical Information
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CAS No. 2938991-80-9
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Appearance Solid
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Molecular Weight 688.66
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Formula C34H31F3N8O5
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Color White to off-white
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SMILES
O=C(C1=CC(O)=CC=C1O)O.FC(F)(C2=CN(C(C)C)C(C3=CC=C(CN4N=CC5=C4N=C(C6=C(C7CC7)N=CN=C6OC)N=C5)C=C3)=N2)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Nucleic Acids Res
USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during replication stress. [Abstract]2024 Mar 21;52(5):2340-2354. PMID: 38180818
Solvent & Solubility
DMSO : 100 mg/mL (145.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4521 mL | 7.2605 mL | 14.5210 mL | 36.3024 mL |
| 5 mM | 0.2904 mL | 1.4521 mL | 2.9042 mL | 7.2605 mL | |
| 10 mM | 0.1452 mL | 0.7260 mL | 1.4521 mL | 3.6302 mL | |
| 15 mM | 0.0968 mL | 0.4840 mL | 0.9681 mL | 2.4202 mL | |
| 20 mM | 0.0726 mL | 0.3630 mL | 0.7260 mL | 1.8151 mL | |
| 25 mM | 0.0581 mL | 0.2904 mL | 0.5808 mL | 1.4521 mL | |
| 30 mM | 0.0484 mL | 0.2420 mL | 0.4840 mL | 1.2101 mL | |
| 40 mM | 0.0363 mL | 0.1815 mL | 0.3630 mL | 0.9076 mL | |
| 50 mM | 0.0290 mL | 0.1452 mL | 0.2904 mL | 0.7260 mL | |
| 60 mM | 0.0242 mL | 0.1210 mL | 0.2420 mL | 0.6050 mL | |
| 80 mM | 0.0182 mL | 0.0908 mL | 0.1815 mL | 0.4538 mL | |
| 100 mM | 0.0145 mL | 0.0726 mL | 0.1452 mL | 0.3630 mL |
KSQ-4279 gentisate Related Classifications
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