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Cat. No.: HY-139133

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L-NASPA

L-NASPA is a ophosphatidic acid (LPA) inhibitor useful in the study of platelet activation.

For research use only. We do not sell to patients.

CAS No.: 155915-46-1
Formula: C₁₉H₃₈NO₇P
Molecular Weight:423.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

L-NASPA Chemical Structure

CAS No.: 155915-46-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

L-NASPA is a ophosphatidic acid (LPA) inhibitor useful in the study of platelet activation^[1].

All LPL Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
RH7777	EC₅₀	1600 nM Compound: Ser-PA	Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor	[PMID: 16033271]
RH7777	EC₅₀	1850 nM Compound: Ser-PA	Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA1 receptor Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA1 receptor	[PMID: 16033271]
RH7777	IC₅₀	>10000 nM Compound: Ser-PA	Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA1 receptor Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA1 receptor	[PMID: 16033271]

Chemical Information

CAS No. 155915-46-1
Molecular Weight 423.48
Formula C₁₉H₃₈NO₇P
SMILES

CCCCCCCCCCCCCCCC(N[C@H](C(O)=O)COP(O)(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Korporaal SJ, et altelet activation by oxidized low density lipoprotein is mediated by CD36 and scavenger receptor-A. Arterioscler Thromb Vasc Biol. 2007 Nov;27(11):2476-83.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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