Lakoochin C
Lakoochin C is an inhibitor of acetylcholinesterase (AChE) (IC50 = 61.86 μM) and butyrylcholinesterase (BChE) (IC50 = 47.21 μM). Lakoochin C may be used in research related to Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 2170152-91-5
- Formula: C30H36O4
- Molecular Weight:460.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
AChE 61.86 μM (IC50) |
BChE 47.21 μM (IC50) |
Chemical Information
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CAS No. 2170152-91-5
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Molecular Weight 460.60
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Formula C30H36O4
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SMILES
C/C(C)=C\CC/C(C)=C/CC1=C2C(C=C(C3=C(C(O)=CC(OC)=C3)C/C=C(C)\C)O2)=CC=C1O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)