LE 28
Based on 1 publication(s) in Google Scholar
LE 28 is a selective and activity-dependent legumain probe. LE 28 becomes fluorescent only upon binding active legumain. LE 28 can be used for research of cancers and inflammatory diseases.
For research use only. We do not sell to patients.
- CAS No.: 1416080-97-1
- Formula: C102H111N10O21S3+
- Molecular Weight:1909.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Publications Citing Use of MedChemExpress (MCE) LE 28
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Biological Activity
LE 28 (2 mg/kg, i.v.) signal is detected around the periphery of the tumors at 30 min, with maximal contrast between tumor and normal tissue achieved after 7 hours in HCT-116 xenograft tumor model[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:HCT-116 xenograft tumor model[1]
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Dosage:2 mg/kg
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Administration:i.v.
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Result:Detected the signal around the periphery of the tumors in as early as 30 min, with maximal contrast between tumor and normal tissue achieved after seven hours, and the signal remained constant up to 28 h.
Chemical Information
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CAS No. 1416080-97-1
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Molecular Weight 1909.22
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Formula C102H111N10O21S3+
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SMILES
O=S(C1=C(C=CC=C1)C2=C(C=CC(N3C4=CC=CC=C4CC3)=C5)C5=[O+]C6=C2C=CC(N7C8=CC=CC=C8CC7)=C6)(N9CCC(CC9)C(NCCCNC(C%10=CC(C)=C(C(C)=C%10)C(OCC([C@H](CC(O)=O)NC([C@H]%11N(CCC%11)C([C@H](CCC(O)=O)NC(CCCCC[N+]%12=C(/C=C/C=C/C=C%13N(C%14=CC=C(S(=O)(O)=O)C=C%14C\%13(C)C)CC)C(C)(C)C%15=CC(S(=O)([O-])=O)=CC=C%12%15)=O)=O)=O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Purity & Documentation
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Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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