- Lipids
- Sphingolipids
- Neutral Glycosphingolipids
Neutral Glycosphingolipids
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Neutral Glycosphingolipids (83)
- Formula: C44H85NO8
- Molecular Weight: 756.15
C20 Galactosyl(?) ceramide (d18:1/20:0) is a β-Glucosyl ceramide.
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- Formula: C43H81NO9
- Molecular Weight: 756.10
Cerebroside D, a glycoceramide compound, improves experimental colitis in mice with multiple targets against activated T lymphocytes.
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- Formula: C48H91NO8
- Molecular Weight: 810.26
βGlcCer is a glycosphingolipid. βGlcCer directly increases the development and PKCα and PKCδ activation in mouse bone marrow-derived DCs (BMDCs). β-GlcCer accumulating in Gaucher disease activates microglia through macrophage-inducible C-type lectin (Mincle) to induce phagocytosis of living neurons, which exacerbates Gaucher symptoms.
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- Formula: C40H77NO8
- Molecular Weight: 700.04
C16 Galactosylceramide is a sphingolipid compound. C16 Galactosylceramide participates in the physiological processes of lipid metabolism and immune regulation in cells. C16 Galactosylceramide can be used in the study of diabetes.
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- Formula: C52H97NO18
- Molecular Weight: 1024.32
Gb3 (d18:1/16:0) (Compound 1) is the Pk antigen of the P blood group system. Gb3 (d18:1/16:0) acts as a cell surface receptor. Gb3 (d18:1/16:0) is used for research on Burkitt's lymphoma, teratocarcinoma, embryonal carcinoma, and Fabry's disease.
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- Formula: C50H95NO13
- Molecular Weight: 918.29
LacCer (d18:1/20:0) is a lipid whose level is closely associated with atherosclerosis and cardiovascular diseases.
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- Formula: C52H99NO13
- Molecular Weight: 946.34
Lc2Cer(d18:1, 22:0) is a lactosylceramide containing d18:1, C22:0 ceramides. Lc2Cer(d18:1, 22:0) can be used for renal cortical epithelial cell research.
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- Formula: C48H91NO13
- Molecular Weight: 890.24
D-lactosyl-β-1,1′ N-stearoyl-D-erythro-sphingosine is a neutral glycolipid.
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- Formula: C47H91NO8
- Molecular Weight: 798.23
C23 Glucosyl(β) ceramide (d18:1/23:0) is a β-Glucosyl ceramide.
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- Formula: C36H63NO8
- Molecular Weight: 637.89
C2 Adamantanyl galactosylceramide (AdaGalCer) (d18:1/2:0) is a bioactive sphingolipid. C2 Adamantanyl galactosylceramide (d18:1/2:0) stimulates glucocerebrosidase activity in vitro. C2 Adamantanyl galactosylceramide (d18:1/2:0) inhibits microsomal LacCer and Gb3 synthase, and inhibits cell sulfatide synthesis. C2 Adamantanyl galactosylceramide (d18:1/2:0) reduces glucosylceramide (GlcCer) levels in normal and lysosomal storage disease (LSD) cells. C2 Adamantanyl galactosylceramide (d18:1/2:0) acts as a substrate for A4GALT and is able to lower Gb3 levels with an IC50 concentration of 40 μM in fabry disease cells.
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- Formula: C48H83NO18
- Molecular Weight: 962.17
C2 Adamantanyl globotriaosylceramide (d18:1/2:0) (AdaGb3), a water-soluble globotriaosylceramide analog, is a bioactive sphingolipid. C2 Adamantanyl globotriaosylceramide (d18:1/2:0) reverses MDR1-MDCK cell drug resistance. C2 Adamantanyl globotriaosylceramide (d18:1/2:0) has high affinity for verotoxin (VT).
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- Formula: C54H98D3NO18
- Molecular Weight: 1055.39
C18 Globotriaosylceramide-d3 is deuterium labeled Gb3(18:1/18:0). Gb3(18:1/18:0) (C18 Globotriaosylceramide (d18:1/18:0)) is an ester product.
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- Formula: C39H68D7NO8
- Molecular Weight: 693.06
C15 Glucosyl(β) ceramide-d7 is deuterium labeled C15 Glucosyl(β) ceramide.
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- Formula: C84H141D7N4O39
- Molecular Weight: 1845.12
C18:0-d7 GD1b Ceramide (d18:1/18:0-d7) is the deuterated-labeled C18:0 GD1b Ceramide (d18:1/18:0), synthetic (HY-167597). C18:0 GD1b Ceramide (d18:1/18:0), synthetic is a synthetic ganglioside. C18:0 GD1b Ceramide (d18:1/18:0), synthetic is a Ganglioside GD1b derivative and a high-purity research standard. C18:0 GD1b Ceramide (d18:1/18:0), synthetic can be used for research on atopic dermatitis and Alzheimer's disease.
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- Formula: C62H107D7N2O23
- Molecular Weight: 1262.61
C18:0-d7 GB4 Ceramide (d18:1/18:0-d7) is deuterium labeled C18:0 GB4 Ceramide (d18:1/18:0).
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- Formula: C42H46D35NO8
- Molecular Weight: 763.31
β-Galactosyl-C18-ceramide-d35 is deuterium labeled β-Galactosyl-C18-ceramide. β-Galactosyl-C18-ceramide is a bioactive molecule that promotes the regulation of nerve cells, regulates protein kinase C activity, and affects hormone receptors. β-Galactosyl-C18-ceramide is widely used in neuroscience research to explore its effects on nerve cell growth and function. The regulatory function of β-Galactosyl-C18-ceramide makes it a potential application prospect in compound development and disease inhibition.
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- Formula: C42H74D5NO8
- Molecular Weight: 731.11
C18:1 Glucosyl ceramide-d5 is deuterium labeled C18:1 Glucosyl ceramide.
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- Formula: C37H66NO18
- Molecular Weight: 812.92
Globotriaosylceramide (non-hydroxy) (porcine RBC) is a glycosphingolipid found in the cell membranes of mammals. Globotriaosylceramide (non-hydroxy) (porcine RBC) is the core pathogenic molecule of Fabry disease, and its level can be downregulated by supplementing α-galactosidase A. Globotriaosylceramide (non-hydroxy) (porcine RBC) amplifies B-cell receptor signals by regulating the localization of co-receptor CD19, and can be used as a vaccine adjuvant, capable of guiding the generation of broad-spectrum and cross-protective antibody responses. Globotriaosylceramide (non-hydroxy) (porcine RBC) promotes wound healing and reduces scar formation by regulating fibroblast heterogeneity.
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- Formula: C50H97N3O8
- Molecular Weight: 868.32
α-GalCer analog 8 is a triazole derivative of α-Galactosylceramide (HY-102022). α-Galactosylceramide is a synthetic glycolipid with antitumorial and immunostimulatory.
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- Formula: C52H88D9NO18
- Molecular Weight: 1033.38
Gb3(d18:1/16:0)-d9 is deuterium labeled Gb3(d18:1/16:0) (HY-156209). Gb3 (d18:1/16:0) (Compound 1) is the Pk antigen of the P blood group system. Gb3 (d18:1/16:0) acts as a cell surface receptor. Gb3 (d18:1/16:0) is used for research on Burkitt's lymphoma, teratocarcinoma, embryonal carcinoma, and Fabry's disease.
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