2. GPCR/G Protein
  3. Adenosine Receptor
  4. LUF5437

LUF5437 is a potent and selective adenosine A1 receptor antagonist with a rat Ki of 7.3 nM. LUF5437 can be used for research on cardiovascular and neurological diseases.

For research use only. We do not sell to patients.

LUF5437

LUF5437 Chemical Structure

CAS No. : 331472-34-5

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LUF5437 Related Antibodies

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Adenosine A1 receptor (A1R) Adenosine A2A receptor (A2AR) Adenosine A2B receptor (A2BR) Adenosine A3 receptor (A3R)

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Description

LUF5437 is a potent and selective adenosine A1 receptor antagonist with a rat Ki of 7.3 nM. LUF5437 can be used for research on cardiovascular and neurological diseases[1].

IC50 & Target[1]

rA1

7.3 nM (Ki)

rA2A

0.57 μM (Ki)

hA3

0.13 μM (Ki)

In Vitro

LUF5437 (Compound 8h) acts as a potent and selective adenosine A1 receptor antagonist, with a Ki of 7.3 nM at rat adenosine A1 receptors[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

LUF5437 Related Antibodies
Molecular Weight

297.33

Formula

C15H11N3O2S
CAS No.
SMILES

O=C(NC1=NC(C2=CC=CC=C2)=NS1)C3=CC=C(O)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LUF5437 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LUF5437331472-34-5LUF 5437LUF-5437Adenosine ReceptorP1 receptorHEK 293 cellsadenosine A2Areceptorrathumanadenosine A3 receptoradenosine A1 receptorInhibitorinhibitorinhibit

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