MARY15
Based on 1 Customer Validation
MARY15 is a pyridinylpiperazine-based derivative of MARY1. MARY15 activates uncoupled mitochondrial respiration and upregulates p-AKT (S473) phosphorylation in renal proximal tubule cells.
For research use only. We do not sell to patients.
- Purity: 99.97%
- CAS No.: 3107758-65-3
- Formula: C19H18F3N3O2
- Molecular Weight:377.36
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
MARY15 (30 nM; 24 h) activates uncoupled mitochondrial respiration in renal proximal tubule cells, as measured by FCCP-OCR[1].
MARY15 (30 nM; 1 h) upregulates p-AKT (S473) phosphorylation in renal proximal tubule cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Renal proximal tubule cells (RPTCs)
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Concentration:30 nM
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Incubation Time:1 h
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Result:Significantly increased phosphorylation levels of AKT at Ser473.
Chemical Information
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CAS No. 3107758-65-3
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Appearance Solid
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Molecular Weight 377.36
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Formula C19H18F3N3O2
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Color White to off-white
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SMILES
O=C(NC1=CC=CC(C(N2CCN(C)CC2)=O)=C1)C3=C(F)C=C(F)C=C3F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)