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  2. Thyroid Hormone Receptor
  3. MB-07344

MB-07344 

Cat. No.: HY-19513
Handling Instructions

MB-07344 is a thyroid hormone receptor (TR)-β agonist with a binding affinity Ki of 2.17 nM.

For research use only. We do not sell to patients.

MB-07344 Chemical Structure

MB-07344 Chemical Structure

CAS No. : 852947-39-8

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Description

MB-07344 is a thyroid hormone receptor (TR)-β agonist with a binding affinity Ki of 2.17 nM[1].

IC50 & Target

Ki: 2.17 nM (Thyroid hormone receptor-β)[1]

In Vivo

MB-07344 (0.05 mg/kg; given i.v., 3 times per week for 3 weeks) results in adjunctive and additive activity when given in combination with atorvastatin in normal rabbits[1].

Animal Model: Normal rabbits[1]
Dosage: 0.05 mg/kg
Administration: Given i.v., 3 times per week for 3 weeks
Result: Combination with atorvastatin further reduced cholesterol.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

364.37

Formula

C₁₉H₂₅O₅P

CAS No.

852947-39-8

SMILES

CC1=C(CC2=CC=C(O)C(C(C)C)=C2)C(C)=CC(OCP(O)(O)=O)=C1

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
MB-07344
Cat. No.:
HY-19513
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MB-07344

Cat. No.: HY-19513