Mc-Pro-PAB-MMAE
Based on 1 Customer Validation
Mc-Pro-PAB-MMAE is a Drug-Linker Conjugate for ADC. Mc-Pro-PAB-MMAE consists of Monomethyl auristatin E (HY-15162) and a linker. Mc-Pro-PAB-MMAE can be used for synthesis of ADCs.
For research use only. We do not sell to patients.
- Purity: 99.16%
- CAS No.: 2766450-03-5
- Formula: C64H95N9O14
- Molecular Weight:1214.49
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Chemical Information
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CAS No. 2766450-03-5
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Appearance Solid
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Molecular Weight 1214.49
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Formula C64H95N9O14
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Color White to off-white
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SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H]4N(CCC4)C(CNC(CCCCCN5C(C=CC5=O)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (82.34 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8234 mL | 4.1170 mL | 8.2339 mL | 20.5848 mL |
| 5 mM | 0.1647 mL | 0.8234 mL | 1.6468 mL | 4.1170 mL | |
| 10 mM | 0.0823 mL | 0.4117 mL | 0.8234 mL | 2.0585 mL | |
| 15 mM | 0.0549 mL | 0.2745 mL | 0.5489 mL | 1.3723 mL | |
| 20 mM | 0.0412 mL | 0.2058 mL | 0.4117 mL | 1.0292 mL | |
| 25 mM | 0.0329 mL | 0.1647 mL | 0.3294 mL | 0.8234 mL | |
| 30 mM | 0.0274 mL | 0.1372 mL | 0.2745 mL | 0.6862 mL | |
| 40 mM | 0.0206 mL | 0.1029 mL | 0.2058 mL | 0.5146 mL | |
| 50 mM | 0.0165 mL | 0.0823 mL | 0.1647 mL | 0.4117 mL | |
| 60 mM | 0.0137 mL | 0.0686 mL | 0.1372 mL | 0.3431 mL | |
| 80 mM | 0.0103 mL | 0.0515 mL | 0.1029 mL | 0.2573 mL |