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Cat. No.: HY-106074

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Mexiprostil

(Synonyms: MDL 646)

Mexiprostil (MDL 646) is an orally active gastric protectant, being a synthetic analogue of Prostaglandin E1 (HY-B0131). Mexiprostil exhibits significant inhibition of gastric acid secretion caused by Histamine (HY-B1204) and Bethanechol (HY-B0406) in rats, dogs, and cats. Mexiprostil can also inhibit the increase in gastric acid secretion caused by Pentagastrin (HY-A0261) in cats, while it does not have this effect in dogs and rats. Mexiprostil does not cause pregnancy termination. Mexiprostil can be used for research on gastric ulcers.

For research use only. We do not sell to patients.

CAS No.: 88980-20-5
Formula: C₂₃H₄₀O₆
Molecular Weight:412.56

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Mexiprostil Chemical Structure

CAS No.: 88980-20-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 88980-20-5
Molecular Weight 412.56
Formula C₂₃H₄₀O₆
SMILES

CCCCC(OC)(C)[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CCCCCCC(OC)=O
Synonyms

MDL 646
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Müller P, et al. An alprostadil analogue and human gastric secretion. A double-blind placebo-controlled study of the effects of a capsule and tablet formulation. Arzneimittelforschung. 1989 Jul;39(7):809-11. [Content Brief]

[2]. Scarpignato C, et al. Action of MDL 646, a new synthetic prostaglandin, on gastric acid secretion of some experimental animals. Res Commun Chem Pathol Pharmacol. 1983 Feb;39(2):211-28. [Content Brief]

[3]. Galliani G, et al. Studies on the luteolytic activity of MDL-646, a new gastroprotective PGE1 analogue, in the hamster. Prostaglandins. 1984 Apr;27(4):583-90. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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