Mirin (Standard)

Mirin (Standard) is the analytical standard of Mirin (HY-19959). This product is intended for research and analytical applications. Mirin is a potent Mre11-Rad50-Nbs1 (MRN) complex inhibitor. Mirin prevents MRN-dependent activation of ATM (IC50=12 μM) without affecting ATM protein Kinase activity, and it inhibits Mre11-associated exonuclease activity. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells. Mirin prevents ATM activation in response to DNA double-strand breaks (DSBs) and blocks homology-directed repair (HDR) in mammalian cells.

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  • CAS. Nr.: 1198097-97-0
  • Formel: C10H8N2O2S
  • Molecular Weight:220.25
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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