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ML230 (Synonyms: CID44640177; SID 88095709)

Cat. No.: HY-111678
Handling Instructions

ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively.

For research use only. We do not sell to patients.

ML230 Chemical Structure

ML230 Chemical Structure

CAS No. : 1776055-05-0

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Estimated Time of Arrival: December 31
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Description

ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively[1].

IC50 & Target

EC50: ABCG2 (0.13 μM)[1]

Molecular Weight

439.47

Formula

C₂₅H₂₁N₅O₃

CAS No.

1776055-05-0

SMILES

O=C(C1=COC=C1)N2CCN(C3=CC(C4=CC=CO4)=NC5=CC(C6=CC=CC=C6)=NN53)CC2

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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ML230
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