2. Metabolic Enzyme/Protease
  3. Lipoxygenase
  4. MLS000545091

MLS000545091 is a potent and selective lipoxygenase-2 (LOX-2) inhibitor with an IC50 value of 2.6 μM for h15-LOX-2.

For research use only. We do not sell to patients.

MLS000545091 Chemical Structure

MLS000545091 Chemical Structure

CAS No. : 322666-76-2

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1 mg USD 120 In-stock
5 mg USD 260 In-stock
10 mg USD 420 In-stock
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Description

MLS000545091 is a potent and selective lipoxygenase-2 (LOX-2) inhibitor with an IC50 value of 2.6 μM for h15-LOX-2[1].

Molecular Weight

262.73

Formula

C14H15ClN2O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC=C(C=C1)C2=NN=C(O2)C3CCCCC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 20.83 mg/mL (79.28 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8062 mL 19.0309 mL 38.0619 mL
5 mM 0.7612 mL 3.8062 mL 7.6124 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8062 mL 19.0309 mL 38.0619 mL 95.1547 mL
5 mM 0.7612 mL 3.8062 mL 7.6124 mL 19.0309 mL
10 mM 0.3806 mL 1.9031 mL 3.8062 mL 9.5155 mL
15 mM 0.2537 mL 1.2687 mL 2.5375 mL 6.3436 mL
20 mM 0.1903 mL 0.9515 mL 1.9031 mL 4.7577 mL
25 mM 0.1522 mL 0.7612 mL 1.5225 mL 3.8062 mL
30 mM 0.1269 mL 0.6344 mL 1.2687 mL 3.1718 mL
40 mM 0.0952 mL 0.4758 mL 0.9515 mL 2.3789 mL
50 mM 0.0761 mL 0.3806 mL 0.7612 mL 1.9031 mL
60 mM 0.0634 mL 0.3172 mL 0.6344 mL 1.5859 mL
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MLS000545091 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MLS000545091322666-76-2MLS 000545091MLS-000545091LipoxygenaseLOXInhibitorinhibitorinhibit

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