2. Metabolic Enzyme/Protease
  3. MMP
  4. MMP-7-IN-3

MMP-7-IN-3 is a potent and selective inhibitor of MMP-7. MMP-7-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction.

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MMP-7-IN-3

MMP-7-IN-3 Estructura química

No. CAS : 2865097-58-9

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  

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MMP-7-IN-3 Related Antibodies

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MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8 MMP-19

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Descripciòn

MMP-7-IN-3 is a potent and selective inhibitor of MMP-7. MMP-7-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction[1].

Peso molecular

818.26

Fòrmula

C34H43ClF3N7O9S
No. CAS
Appearance

Solid

Color

White to off-white

Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad
In Vitro: 

DMSO : 100 mg/mL (122.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2221 mL 6.1105 mL 12.2211 mL
5 mM 0.2444 mL 1.2221 mL 2.4442 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2221 mL 6.1105 mL 12.2211 mL 30.5526 mL
5 mM 0.2444 mL 1.2221 mL 2.4442 mL 6.1105 mL
10 mM 0.1222 mL 0.6111 mL 1.2221 mL 3.0553 mL
15 mM 0.0815 mL 0.4074 mL 0.8147 mL 2.0368 mL
20 mM 0.0611 mL 0.3055 mL 0.6111 mL 1.5276 mL
25 mM 0.0489 mL 0.2444 mL 0.4888 mL 1.2221 mL
30 mM 0.0407 mL 0.2037 mL 0.4074 mL 1.0184 mL
40 mM 0.0306 mL 0.1528 mL 0.3055 mL 0.7638 mL
50 mM 0.0244 mL 0.1222 mL 0.2444 mL 0.6111 mL
60 mM 0.0204 mL 0.1018 mL 0.2037 mL 0.5092 mL
80 mM 0.0153 mL 0.0764 mL 0.1528 mL 0.3819 mL
100 mM 0.0122 mL 0.0611 mL 0.1222 mL 0.3055 mL
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MMP-7-IN-3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MMP-7-IN-32865097-58-9MMPMatrix metalloproteinasesMMP-7 InhibitorKidney fibrosisUnilateral ureteral obstruction mouse modelInhibitorinhibitorinhibit

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Nombre del producto:
MMP-7-IN-3
Cat. No.:
HY-156430
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