(+)-Mollisacacidin
(+)-Mollisacacidin is a flavan compound found in the root bark of Albizia glaberrima. (+)-Mollisacacidin exhibits no significant antiproliferative effect on cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 967-27-1
- Formula: C15H14O6
- Molecular Weight:290.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
(+)-Mollisacacidin (Compound 2) (20-50 μM; 2 days) shows no significant antiproliferative activity against HL60 human leukemia cells at 20 μM or HeLa human cervical cancer cells at 50 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
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Cell Line:HL60 human leukemia cells, HeLa human cervical cancer cells
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Concentration:20 μM (HL60 cells); 50 μM (HeLa cells)
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Incubation Time:2 days
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Result:Resulted in 99.8% average cell viability in HL60 cells, indicating no significant antiproliferative effect.
Resulted in 108.6% average cell viability in HeLa cells, indicating no significant antiproliferative effect.
Chemical Information
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CAS No. 967-27-1
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Molecular Weight 290.27
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Formula C15H14O6
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SMILES
O[C@@H]1[C@H](OC=2C([C@H]1O)=CC=C(O)C2)C3=CC(O)=C(O)C=C3
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(+)-Mollisacacidin Related Classifications
HY-N13130 Related Classifications
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