2. MPDC

MPDC is a potent and competitive inhibitor of the Na+-dependent high-affinity glutamate transporter in forebrain synaptosomes.

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MPDC Chemical Structure

MPDC Chemical Structure

CAS No. : 159262-32-5

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MPDC Related Antibodies

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Description

MPDC is a potent and competitive inhibitor of the Na+-dependent high-affinity glutamate transporter in forebrain synaptosomes[1].

IC50 & Target

Glutamate transporter[1].
Molecular Weight

171.15

Formula

C7H9NO4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@@H]1[C@@]2([H])[C@@H](C(O)=O)[C@@]2([H])CN1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 8.33 mg/mL (48.67 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8428 mL 29.2141 mL 58.4283 mL
5 mM 1.1686 mL 5.8428 mL 11.6857 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.8428 mL 29.2141 mL 58.4283 mL 146.0707 mL
5 mM 1.1686 mL 5.8428 mL 11.6857 mL 29.2141 mL
10 mM 0.5843 mL 2.9214 mL 5.8428 mL 14.6071 mL
15 mM 0.3895 mL 1.9476 mL 3.8952 mL 9.7380 mL
20 mM 0.2921 mL 1.4607 mL 2.9214 mL 7.3035 mL
25 mM 0.2337 mL 1.1686 mL 2.3371 mL 5.8428 mL
30 mM 0.1948 mL 0.9738 mL 1.9476 mL 4.8690 mL
40 mM 0.1461 mL 0.7304 mL 1.4607 mL 3.6518 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MPDC159262-32-5Inhibitorinhibitorinhibit

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