2. PI3K/Akt/mTOR
  3. mTOR
  4. mTOR inhibitor-11

mTOR inhibitor-11 (Compound 9) is a brain-penetrant mTOR inhibitor (IC50: 21 nM for pS6). mTOR inhibitor-11 also inhibits pCHK1 and PDE4D with IC50s of 17.2 and 17.0 μM. mTOR inhibitor-11 can be used for research of CNS disease.

For research use only. We do not sell to patients.

mTOR inhibitor-11 Chemical Structure

mTOR inhibitor-11 Chemical Structure

CAS No. : 3033409-32-1

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mTOR inhibitor-11 Related Antibodies

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Description

mTOR inhibitor-11 (Compound 9) is a brain-penetrant mTOR inhibitor (IC50: 21 nM for pS6). mTOR inhibitor-11 also inhibits pCHK1 and PDE4D with IC50s of 17.2 and 17.0 μM. mTOR inhibitor-11 can be used for research of CNS disease[1].

Molecular Weight

394.47

Formula

C21H26N6O2
CAS No.
SMILES

C[C@@H]1COCCN1C2=C3N=C(C4=NC=CC=C4)NC3=NC(N5[C@@H](C)COCC5)=C2
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Room temperature in continental US; may vary elsewhere.
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mTOR inhibitor-11 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

mTOR inhibitor-113033409-32-1mTOR inhibitor11mTOR inhibitor 11mTORMammalian target of RapamycinCNS diseasepCHK1PDE4DpS6Inhibitorinhibitorinhibit

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