Creatine-d3
Based on 2 publication(s) in Google Scholar
Creatine-d3 is the deuterium labeled Creatine (HY-W010388). Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain.
For research use only. We do not sell to patients.
- Purity: 99.92%
- CAS No.: 143827-19-4
- Formula: C4H6D3N3O2
- Molecular Weight:134.15
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Creatine-d3
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 143827-19-4
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Unlabeled Cas 57-00-1
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Appearance Solid
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Molecular Weight 134.15
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Formula C4H6D3N3O2
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Color White to off-white
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SMILES
OC(CN(C([2H])([2H])[2H])C(N)=N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
2025 Jan;12(2):e2411015. PMID: 39569747 -
Phytomedicine
The hidden potential of solasonine: Targeting non-small cell lung cancer (NSCLC) metastasis through GATM and Smad2 pathways. [Abstract]2025 Apr:139:156455. PMID: 39922150
Solvent & Solubility
H2O : 16.67 mg/mL (124.26 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Nouioua S, et al. Creatine deficiency syndrome. A treatable myopathy due to arginine-glycine amidinotransferase (AGAT) deficiency. Neuromuscul Disord. 2013 Aug;23(8):670-4. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.4543 mL | 37.2717 mL | 74.5434 mL | 186.3586 mL |
| 5 mM | 1.4909 mL | 7.4543 mL | 14.9087 mL | 37.2717 mL | |
| 10 mM | 0.7454 mL | 3.7272 mL | 7.4543 mL | 18.6359 mL | |
| 15 mM | 0.4970 mL | 2.4848 mL | 4.9696 mL | 12.4239 mL | |
| 20 mM | 0.3727 mL | 1.8636 mL | 3.7272 mL | 9.3179 mL | |
| 25 mM | 0.2982 mL | 1.4909 mL | 2.9817 mL | 7.4543 mL | |
| 30 mM | 0.2485 mL | 1.2424 mL | 2.4848 mL | 6.2120 mL | |
| 40 mM | 0.1864 mL | 0.9318 mL | 1.8636 mL | 4.6590 mL | |
| 50 mM | 0.1491 mL | 0.7454 mL | 1.4909 mL | 3.7272 mL | |
| 60 mM | 0.1242 mL | 0.6212 mL | 1.2424 mL | 3.1060 mL | |
| 80 mM | 0.0932 mL | 0.4659 mL | 0.9318 mL | 2.3295 mL | |
| 100 mM | 0.0745 mL | 0.3727 mL | 0.7454 mL | 1.8636 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Creatine-d3 Related Classifications
HY-W010388S1 Related Classifications
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