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Cat. No.: HY-W040046

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Nafoxidine hydrochloride

(Synonyms: Nafoxidene hydrochloride)

Nafoxidine hydrochloride is a non-steroidal estrogen receptor antagonist with antitumor activity for breast cancer.

For research use only. We do not sell to patients.

CAS No.: 1847-63-8
Formula: C₂₉H₃₂ClNO₂
Molecular Weight:462.02

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Nafoxidine hydrochloride Chemical Structure

CAS No.: 1847-63-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Nafoxidine hydrochloride is a non-steroidal estrogen receptor antagonist with antitumor activity for breast cancer^[1]^[2]^[3].

All Estrogen Receptor/ERR Isoforms :

Chemical Information

CAS No. 1847-63-8
Molecular Weight 462.02
Formula C₂₉H₃₂ClNO₂
SMILES

[H]Cl.COC1=CC2=C(C=C1)C(C3=CC=C(C=C3)OCCN4CCCC4)=C(C5=CC=CC=C5)CC2
Synonyms

Nafoxidene hydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sato M, Rippy MK, Bryant HU. Raloxifene, tamoxifen, nafoxidine, or estrogen effects on reproductive and nonreproductive tissues in ovariectomized rats. FASEB J. 1996;10(8):905-912. [Content Brief]

[2]. De Lorenzo MS, Farina HG, Alonso DF, Gomez DE. Role of protein kinase C-dependent signaling pathways in the antiangiogenic properties of nafoxidine. Anticancer Res. 2004;24(3a):1737-1743. [Content Brief]

[3]. Yaz G, Kabadere S, Oztopçu P, Durmaz R, Uyar R. Comparison of the antiproliferative properties of antiestrogenic drugs (nafoxidine and clomiphene) on glioma cells in vitro. Am J Clin Oncol. 2004;27(4):384-388. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Nafoxidine hydrochloride

All Estrogen Receptor/ERR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Nafoxidine hydrochloride Related Classifications

HY-W040046 Related Classifications