Nasunin
Based on 1 publication(s) in Google Scholar
Nasunin, an antioxidant anthocyanin, possesses antiangiogenic activity.
For research use only. We do not sell to patients.
- Purity: 99.34%
- CAS No.: 28463-30-1
- Formula: C42H47ClO23
- Molecular Weight:955.26
-
Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Nasunin
More
Biological Activity
Nasunin at higher 10 µM suppresses microvessel outgrowth in an ex vivo angiogenesis assay using a rat aortic ring[1].
Nasunin suppresses HUVEC proliferation in a dose-dependent manner (50-200 µM)[1].
Nasunin diminishes LPS-induced nuclear factor-κB (NF-κB) activation by suppressing the
degradation of inhibitor of κB-α and nuclear translocation of p65 subunit of NF-κB. Nasunin also attenuates the phosphorylation of Akt and p38, signaling molecules involved in pro-inflammatory mediator production[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 28463-30-1
-
Appearance Solid
-
Molecular Weight 955.26
-
Formula C42H47ClO23
-
Color Brown to black
-
SMILES
O[C@H]([C@@H]([C@H]([C@@H](O1)C)OC(/C=C/C2=CC=C(C=C2)O)=O)O)[C@@H]1OC[C@H]([C@H]([C@@H]([C@H]3O)O)O)O[C@H]3OC4=CC(C(O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO)=CC(O)=C6)=C6[O+]=C4C7=CC(O)=C(C(O)=C7)O.[Cl-]
-
Synonyms
Delphinidin-3-(p-coumaroylrutinoside)-5-glucoside
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Biochim Biophys Acta Mol Basis Dis
Neutrophil-derived thrombospondin-1 (THBS1) drives type 2 diabetes-induced osteoporosis via CD36-PPARγ-POU2F2 signaling. [Abstract]2025 Dec 15;1872(3):168139. PMID: 41407214
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[1]. Kiminori Matsubara, et al. Antiangiogenic activity of nasunin, an antioxidant anthocyanin, in eggplant peels. J Agric Food Chem. 2005 Aug 10;53(16):6272-5. [Content Brief]
[2]. Wataru Komatsu, et al. Nasunin inhibits the lipopolysaccharide-induced pro-inflammatory mediator production in RAW264 mouse macrophages by suppressing ROS-mediated activation of PI3 K/Akt/NF-κB and p38 signaling pathways. Biosci Biotechnol Biochem. 2017 O [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nasunin Related Classifications
HY-N9396 Related Classifications
Powered by Bioz