1. Metabolic Enzyme/Protease
  2. Glucosidase
  3. NCGC 607

NCGC607 is a noninhibitory chaperone of glucocerebrosidase (Gcase).

For research use only. We do not sell to patients.

NCGC 607 Chemical Structure

NCGC 607 Chemical Structure

CAS No. : 1462267-07-7

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1 mg USD 54 In-stock
5 mg USD 170 In-stock
10 mg USD 270 In-stock
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Description

NCGC607 is a noninhibitory chaperone of glucocerebrosidase (Gcase)[1].

Molecular Weight

543.35

Formula

C24H22IN3O4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NCC(N(C)C1=CC=CC=C1)=O)C2=CC=CC=C2OCC(NC3=CC=C(I)C=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (115.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8404 mL 9.2022 mL 18.4043 mL
5 mM 0.3681 mL 1.8404 mL 3.6809 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8404 mL 9.2022 mL 18.4043 mL 46.0109 mL
5 mM 0.3681 mL 1.8404 mL 3.6809 mL 9.2022 mL
10 mM 0.1840 mL 0.9202 mL 1.8404 mL 4.6011 mL
15 mM 0.1227 mL 0.6135 mL 1.2270 mL 3.0674 mL
20 mM 0.0920 mL 0.4601 mL 0.9202 mL 2.3005 mL
25 mM 0.0736 mL 0.3681 mL 0.7362 mL 1.8404 mL
30 mM 0.0613 mL 0.3067 mL 0.6135 mL 1.5337 mL
40 mM 0.0460 mL 0.2301 mL 0.4601 mL 1.1503 mL
50 mM 0.0368 mL 0.1840 mL 0.3681 mL 0.9202 mL
60 mM 0.0307 mL 0.1534 mL 0.3067 mL 0.7668 mL
80 mM 0.0230 mL 0.1150 mL 0.2301 mL 0.5751 mL
100 mM 0.0184 mL 0.0920 mL 0.1840 mL 0.4601 mL
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NCGC 607 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NCGC 607
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