2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. NecroX-5 free base

NecroX-5 free base is a derivative of the NecroX, reduces intracellular calcium concentration, and possesses anti-inflammatory and anti-cancer activity.

For research use only. We do not sell to patients.

CAS No. : 1120332-90-2

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NecroX-5 free base Related Antibodies

Top Publications Citing Use of Products

    NecroX-5 free base purchased from MedChemExpress. Usage Cited in: Int Immunopharmacol. 2020 Apr;81:106257.  [Abstract]

    NecroX-5 inhibits the NLRP3 inflammasome activation in macrophages. RAW264.7 cells are firstly pretreated with 20 μM NecroX-5 for 1 h and then stimulated with LPS (1 μg/mL) for 8 h followed by 5 mmol/L of ATP for 30 min. Quantification of western blot in panen D.

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    N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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    Description

    NecroX-5 free base is a derivative of the NecroX, reduces intracellular calcium concentration, and possesses anti-inflammatory and anti-cancer activity.

    Molecular Weight

    453.60

    Formula

    C25H31N3O3S
    CAS No.
    SMILES

    O=S1(CCN(CC1)CC2=CC3=C(C(NCC4CCOCC4)=C2)NC(C5=CC=CC=C5)=C3)=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    NecroX-5 free base Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    NecroX-51120332-90-2NecroX5NecroX 5Calcium ChannelCa2+ channelsCa channelsInhibitorinhibitorinhibit

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