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NF-κB-IN-5

NF-κB-IN-5 (compound 4d) is an orally active and potent NF-κB inhibitor by interacting directly with NF-κB. NF-κB-IN-5 shows antitumor activity against human cancer cell lines (HCT116, U87-MG, HepG2, BGC823, PC9), with IC50 values of 5.35, 2.81, 2.83, 2.02 and 3.90 μM, respectively. NF-κB-IN-5 induces apoptosis in U87-MG tumor cell and cell cycle arrest in G0/G1 phase.

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  • CAS No.: 2425675-52-9
  • 화학식: C23H27N3O4
  • 분자량:409.48
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • NF-κB-IN-5 Chemical Structure
    NF-κB-IN-5 Chemical Structure
CAS No.: 2425675-52-9
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    NF-κB-IN-5 Chemical Structure
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  • NF-κB-IN-5